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Longevity

NAD+

Nicotinamide Adenine Dinucleotide

99.5%purity
Mol. Weight

663.4 Da

Form

Liquid

Half-Life

~1–2 hours (IV); longer with oral precursors

Storage

Refrigerate at 2–8°C, protect from light

// PAI-2026-05

NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in every living cell. It plays a central role in energy metabolism, DNA repair, and the activation of sirtuins — proteins associated with longevity. NAD+ levels decline significantly with age, and supplementation has been studied for its potential to restore cellular energy, improve mitochondrial function, and slow aging processes.

Anti-AgingPerformanceNeuroprotection

Select Quantity

500 mg · Lyophilized

$121.88

per mg

$0.24

COA Verified
HPLC Tested
Ships in 24h

Mechanism of Action

  • Activates SIRT1/SIRT3 longevity pathways
  • Essential cofactor in mitochondrial ATP production
  • Activates PARP for DNA damage repair
  • Supports CD38 and NAMPT enzyme activity

Amino Acid Sequence

Nicotinamide Adenine Dinucleotide (oxidized form)

Solubility

Liquid formulation — ready to use

Certificate of Analysis

Batch PAI-2026-05 · Issued Jul 26, 2026

HPLC Purity
PASS

99.5%

RP-HPLC · UV 220nm

MS Identity
PASS

Confirmed

LC-MS/MS · ESI+

Endotoxins
PASS

<0.1 EU/mg

LAL method

Microbial
PASS

<10 CFU/g

USP <61>

HPLC Purity Profile

99.5% main peak
99.5%
0%Spec: ≥98.0%100%
TestMethodSpecificationResultStatus
Purity (HPLC)RP-HPLC≥98.0%99.5%PASS
Identity (MS)LC-MS/MSConformsConformsPASS
AppearanceVisualWhite powderConformsPASS
MoistureKarl Fischer≤8.0%4.9%PASS
Residual SolventsGC-HSICH Q3CConformsPASS
EndotoxinsLAL<1 EU/mg<0.1 EU/mgPASS

Testing performed by independent ISO-accredited laboratory. Full chromatograms and spectra available in the downloadable COA document.

Research References

[1]

NAD+ metabolism and its roles in cellular processes

Nat Rev Mol Cell Biol · 2019

For research purposes only. These references are provided for informational use and do not constitute medical advice.

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