MOTS-C
Mitochondrial Open Reading Frame of the 12S rRNA-c
2174.5 Da
Liquid
~1–2 hours
Refrigerate at 2–8°C, protect from light
// PAI-2026-05
MOTS-C
MOTS-C is a mitochondria-derived peptide encoded in the mitochondrial genome. It acts as a metabolic regulator, improving insulin sensitivity, activating AMPK, and enhancing exercise capacity. Research suggests it plays a key role in metabolic homeostasis and may have significant anti-aging and longevity-promoting properties.
Select Quantity
10 mg · Lyophilized
$121.88
per mg
$12.19
Mechanism of Action
- Activates AMPK pathway for metabolic regulation
- Improves insulin sensitivity and glucose uptake
- Enhances mitochondrial function and biogenesis
- Translocates to nucleus under metabolic stress
Amino Acid Sequence
MRWQEMGYIFYPRKLR
Solubility
Liquid formulation — ready to use
Certificate of Analysis
Batch PAI-2026-05 · Issued Jul 26, 2026
99.5%
RP-HPLC · UV 220nm
Confirmed
LC-MS/MS · ESI+
<0.1 EU/mg
LAL method
<10 CFU/g
USP <61>
HPLC Purity Profile
99.5% main peak| Test | Method | Specification | Result | Status |
|---|---|---|---|---|
| Purity (HPLC) | RP-HPLC | ≥98.0% | 99.5% | PASS |
| Identity (MS) | LC-MS/MS | Conforms | Conforms | PASS |
| Appearance | Visual | White powder | Conforms | PASS |
| Moisture | Karl Fischer | ≤8.0% | 3.4% | PASS |
| Residual Solvents | GC-HS | ICH Q3C | Conforms | PASS |
| Endotoxins | LAL | <1 EU/mg | <0.1 EU/mg | PASS |
Testing performed by independent ISO-accredited laboratory. Full chromatograms and spectra available in the downloadable COA document.
Research References
MOTS-C: a mitochondrial-derived peptide regulating metabolism
Cell Metab · 2015
For research purposes only. These references are provided for informational use and do not constitute medical advice.
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