Sermorelin
Sermorelin (GHRH 1-29)
3357.9 Da
Liquid
~10–20 minutes
Refrigerate at 2–8°C, protect from light
// PAI-2026-05
Sermorelin
Sermorelin is a synthetic analogue of the first 29 amino acids of growth hormone-releasing hormone (GHRH). It stimulates the pituitary gland to naturally produce and secrete GH, making it a physiological approach to GH optimization. Research highlights its use for anti-aging, improved body composition, enhanced sleep quality, and recovery.
Select Quantity
10 mg · Lyophilized
$109.69
per mg
$10.97
Mechanism of Action
- Binds GHRH receptor on pituitary somatotrophs
- Stimulates natural, pulsatile GH secretion
- Preserves pituitary GH reserve unlike exogenous GH
- Increases IGF-1 levels downstream
Amino Acid Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
Solubility
Liquid formulation — ready to use
Certificate of Analysis
Batch PAI-2026-05 · Issued Jul 26, 2026
99.5%
RP-HPLC · UV 220nm
Confirmed
LC-MS/MS · ESI+
<0.1 EU/mg
LAL method
<10 CFU/g
USP <61>
HPLC Purity Profile
99.5% main peak| Test | Method | Specification | Result | Status |
|---|---|---|---|---|
| Purity (HPLC) | RP-HPLC | ≥98.0% | 99.5% | PASS |
| Identity (MS) | LC-MS/MS | Conforms | Conforms | PASS |
| Appearance | Visual | White powder | Conforms | PASS |
| Moisture | Karl Fischer | ≤8.0% | 4.9% | PASS |
| Residual Solvents | GC-HS | ICH Q3C | Conforms | PASS |
| Endotoxins | LAL | <1 EU/mg | <0.1 EU/mg | PASS |
Testing performed by independent ISO-accredited laboratory. Full chromatograms and spectra available in the downloadable COA document.
Research References
Sermorelin in adult GH deficiency
J Clin Endocrinol Metab · 1997
For research purposes only. These references are provided for informational use and do not constitute medical advice.
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