Semax
Semax (ACTH 4-7 Pro-Gly-Pro)
813.0 Da
Liquid
~20 minutes (intranasal)
Refrigerate at 2–8°C, protect from light
// PAI-2026-05
Semax
Semax is a synthetic heptapeptide analogue of ACTH(4-7) developed in Russia and used clinically for stroke recovery and cognitive enhancement. It is one of the most well-researched nootropic peptides, with strong evidence for BDNF upregulation, neuroprotection, and enhancement of memory and attention.
Select Quantity
10 mg · Lyophilized
$146.25
per mg
$14.63
Mechanism of Action
- Upregulates BDNF and NGF expression
- Modulates dopaminergic and serotonergic systems
- Neuroprotective via anti-inflammatory pathways
- Enhances hippocampal neuroplasticity
Amino Acid Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Solubility
Liquid formulation — ready to use
Certificate of Analysis
Batch PAI-2026-05 · Issued Jul 26, 2026
99.6%
RP-HPLC · UV 220nm
Confirmed
LC-MS/MS · ESI+
<0.1 EU/mg
LAL method
<10 CFU/g
USP <61>
HPLC Purity Profile
99.6% main peak| Test | Method | Specification | Result | Status |
|---|---|---|---|---|
| Purity (HPLC) | RP-HPLC | ≥98.0% | 99.6% | PASS |
| Identity (MS) | LC-MS/MS | Conforms | Conforms | PASS |
| Appearance | Visual | White powder | Conforms | PASS |
| Moisture | Karl Fischer | ≤8.0% | 3.2% | PASS |
| Residual Solvents | GC-HS | ICH Q3C | Conforms | PASS |
| Endotoxins | LAL | <1 EU/mg | <0.1 EU/mg | PASS |
Testing performed by independent ISO-accredited laboratory. Full chromatograms and spectra available in the downloadable COA document.
Research References
Semax, an ACTH(4-7) analogue, activates BDNF and VEGF expression
J Mol Neurosci · 2006
For research purposes only. These references are provided for informational use and do not constitute medical advice.
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