PT-141
PT-141 (Bremelanotide)
1025.2 Da
Liquid
~2.7 hours
Refrigerate at 2–8°C, protect from light
// PAI-2026-05
PT-141
PT-141 (Bremelanotide) is a synthetic analogue of α-MSH that acts on melanocortin receptors in the central nervous system. Unlike PDE5 inhibitors, it works centrally via hypothalamic pathways to enhance sexual arousal and function in both men and women. It has been studied extensively for hypoactive sexual desire disorder and erectile dysfunction.
Select Quantity
10 mg · Lyophilized
$158.44
per mg
$15.84
Mechanism of Action
- Activates MC3R and MC4R in hypothalamus
- Increases dopamine release in mesolimbic pathway
- Central mechanism independent of vascular effects
- Enhances sexual motivation and arousal
Amino Acid Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Solubility
Liquid formulation — ready to use
Certificate of Analysis
Batch PAI-2026-05 · Issued Jul 27, 2026
99.5%
RP-HPLC · UV 220nm
Confirmed
LC-MS/MS · ESI+
<0.1 EU/mg
LAL method
<10 CFU/g
USP <61>
HPLC Purity Profile
99.5% main peak| Test | Method | Specification | Result | Status |
|---|---|---|---|---|
| Purity (HPLC) | RP-HPLC | ≥98.0% | 99.5% | PASS |
| Identity (MS) | LC-MS/MS | Conforms | Conforms | PASS |
| Appearance | Visual | White powder | Conforms | PASS |
| Moisture | Karl Fischer | ≤8.0% | 4.5% | PASS |
| Residual Solvents | GC-HS | ICH Q3C | Conforms | PASS |
| Endotoxins | LAL | <1 EU/mg | <0.1 EU/mg | PASS |
Testing performed by independent ISO-accredited laboratory. Full chromatograms and spectra available in the downloadable COA document.
Research References
Bremelanotide for hypoactive sexual desire disorder
J Sex Med · 2019
For research purposes only. These references are provided for informational use and do not constitute medical advice.
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